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| Dosages: | Severe staphylococci infection-
Neonate < 1 wk and < 2 kg: 10-15 mg/kg IV q 12-18 h.
Neonate < 1 wk and = 2 kg: 10-15 mg/kg IV q 8-12 h.
Neonate < 1 wk and < 2 kg: 10-15 mg/kg IV q 8-12 h.
Neonate < 1 wk and < 2 kg: 15-20 mg/kg IV q 8 h.
Neonate < 4 wk and < 1.2 kg: 15 mg/kg IV q 24 h.
Infant, child: 4. mg/kg IV qd divided q 6 h or 1.2 gram/m2/day given in divided doses; severe infection: 40-60 mg/kg qd in 4 divided doses. Max 2 gram qd.
Adult: 500 mg IV q 6 h, or 1 gram q 12 h.
Antibiotic-associated pseudomembranous, staphylococci enterocolitis-
Child: 40 mg/kg PO qd divided q 6-8 h × 7-10 day. Max 2 gram/day.
Adult: 125-500 mg PO q 6 h × 7-10 day.
Endocarditis prophylaxis for GI, biliary, GU procedure; surgery prophylaxis in pt allergic to penicillin-
Child: 20 mg/kg IV over 1-2 h; complete infusion within 30 min of procedure. High-risk pt: give with gentamicin.
Adult: 1 gram IV over 1 h, starting 1 h before procedure. High-risk pt: give with gentamicin. |
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